Hereditary Sensory and Autonomic Neuropathy, often abbreviated as HSAN, refers to as many as six different degenerative disorders of the nervous system that involve loss of feeling, particularly in the hands and feet.
HSAN is a rare genetic condition caused by the abnormal functioning of the sensory nerves that control responses to pain and temperature, according to an article in WebMD. In one type of HSAN, HSAN 1, sufferers may have a lack of sensation in their extremities, and may be unable to sweat from those parts of their body unless their body temperature becomes dangerously high.
Sufferers from other types of HSAN may have the opposite problems: they may have pain shooting up through their legs, and they may find that they sweat excessively.
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