Saturday, March 2, 2013

Health Notes: Genetic Links Seen Between Depression, Autism, & other Disorders; Mind-Reading Rats; Public's Help Sought in Curing Cancer; More

Some interesting news from the world of health and medicine:

* Scientists see link in depression and four other disorders: Five disparate mental-health disorders may have a common genetic link, according to a new study that's getting lots of attention. The research has found that a number of genes are shared by people who have major depression, bipolar disorder, schizophrenia, autism, and attention-deficit hyperactivity disorder. The study was published in the edition of The Lancet publishing on Wednesday (abstract).

The researchers found that "four spots in the genome that were more common among those with psychiatric disease, two of which occurred in genes involved in communication between brain cells," according to an article in the Boston Globe. Also, "They also found that genetic risk factors for bipolar disorder and schizophrenia had the most overlap."
They also found that genetic risk factors for bipolar disorder and schizophrenia had the most overlap. - See more at: http://www.boston.com/news/science/blogs/science-in-mind/2013/02/27/autism-schizophrenia-and-other-psychiatric-disorders-share-genetic-underpinnings/I5Rdy7NikMlFvTe8d9BXoL/blog.html#sthash.iwHOygA5.dpuf
They also found that genetic risk factors for bipolar disorder and schizophrenia had the most overlap. - See more at: http://www.boston.com/news/science/blogs/science-in-mind/2013/02/27/autism-schizophrenia-and-other-psychiatric-disorders-share-genetic-underpinnings/I5Rdy7NikMlFvTe8d9BXoL/blog.html#sthash.iwHOygA5.dpuf
four spots in the genome that were more common among those with psychiatric disease, two of which occurred in genes involved in communication between brain cells. - See more at: http://www.boston.com/news/science/blogs/science-in-mind/2013/02/27/autism-schizophrenia-and-other-psychiatric-disorders-share-genetic-underpinnings/I5Rdy7NikMlFvTe8d9BXoL/blog.html#sthash.iwHOygA5.dpuf
found four spots in the genome that were more common among those with psychiatric disease, two of which occurred in genes involved in communication between brain cells.
They also found that genetic risk factors for bipolar disorder and schizophrenia had the most overlap.
- See more at: http://www.boston.com/news/science/blogs/science-in-mind/2013/02/27/autism-schizophrenia-and-other-psychiatric-disorders-share-genetic-underpinnings/I5Rdy7NikMlFvTe8d9BXoL/blog.html#sthash.iwHOygA5.dpuf
found four spots in the genome that were more common among those with psychiatric disease, two of which occurred in genes involved in communication between brain cells.
They also found that genetic risk factors for bipolar disorder and schizophrenia had the most overlap.
- See more at: http://www.boston.com/news/science/blogs/science-in-mind/2013/02/27/autism-schizophrenia-and-other-psychiatric-disorders-share-genetic-underpinnings/I5Rdy7NikMlFvTe8d9BXoL/blog.html#sthash.iwHOygA5.dpuf
found four spots in the genome that were more common among those with psychiatric disease, two of which occurred in genes involved in communication between brain cells.
They also found that genetic risk factors for bipolar disorder and schizophrenia had the most overlap.
- See more at: http://www.boston.com/news/science/blogs/science-in-mind/2013/02/27/autism-schizophrenia-and-other-psychiatric-disorders-share-genetic-underpinnings/I5Rdy7NikMlFvTe8d9BXoL/blog.html#sthash.iwHOygA5.dpuf


Telepathic rats? See for yourself.

* "First mind-reading implant gives rats telepathic power": Now there's a headline that'll get your attention. The New Scientist articles reports that "The world's first brain-to-brain connection has given rats the power to communicate by thought alone."

Although this is an exciting development in brain research (rats on different continents were even able to communicate via the Internet), the article notes that  "the exact information being communicated between the rats' brains is not clear."

* Tech giants seek public's help for cancer cure: British cancer researchers are joining forces with Google, Amazon.com, and Facebook to enlist the public's assistance in finding cures for cancer. Cancer Research U.K. is teaming up with the tech firms to get the public to perform tasks that can help in efforts such as "working out the exact sequence of a tumor's DNA,"according to a BBC News article.

Programmers, game designers, and others are set to meet this week to figure out how to create a game-life way to put the collective eyeballs and computer power of everyday citizens to solve problems in cancer research. The concept is similar to volunteer-computer efforts from the BOINC project, such as SETI@Home and medical-related endeavors such as RNA World and Malariacontrol.net. It's hoped the project will be up and running by summer.

* Coronary calcium indicates stroke risk: A coronary artery calcification score can predict the risk of stroke, independent of other factors, at least in cases of people with lower risk of cardiovascular disease. An article in MedPage Today says that this may or may not change how clinicians work, since it's already been established that stroke and coronary artery disease have some of the same disease processes.

What's more, the measure of calcification is done by an electron-beam CT scan, so any potential benefit of the rest must be weighed against the additional radiation exposure.

Friday, February 1, 2013

FDA Panel Seeks New Limits on Powerful Painkiller Hydrocodone

An advisory panel of the Food and Drug Administration (FDA) has recommended that the agency put tighter restrictions on the common painkiller hydrocodone, an ingredient in brand-name drugs such as Vicodin. The vote of the panel was 19-10: a majority to be sure, but certainly not unanimous.

Hydrocodone/paracetamol tablets
Hydrocodone/paracetamol 5/500 tablets (Mallinckrodt). Photo: Elbreapoly

The panel is calling for hydrocodone, an opioid, to be made a Schedule II drug, which will place it in the same category as morphine, fentanyl, and oxycodone. Hydrocodone is currently in Schedule III.The FDA is likely to follow the panel's advice, according to the New York Times. The agency is seeking to limit widespread abuse of painkillers; the Times article notes that the number of deaths from pain drugs has increased fourfold since 1999.

Among other things, being in the more restrictive Schedule II would mean that hydrocodone prescriptions would be harder to refill (a patient would need to get a new prescription to get a refill). The drug could also not be obtained by faxed prescriptions.

Hydrocodone is the most frequently prescribed pain medication in the U.S., and some experts say it is because of the misconception in the medical community that it is not as dangerous or addictive as Schedule II drugs such as Percocet or methadone.

Other professionals question whether putting hydrocodone in Schedule II would actually limit its abuse, and may make it harder to obtain for patients suffering from pain.

The FDA panel is hoping to make the nation's most-prescribed painkiller less of a killer.

Saturday, January 12, 2013

2013 Flu Outbreak: Know the Signs & Protect Yourself

The 2012-2013 flu season is shaping up to be a very bad one, with widespread flu "activity" reported in 47 states, according to the CDC. New York became the latest state to declare a public health emergency due to the epidemic, but some areas may begin to see fewer cases.

Below the Google flu map are some ways to protect yourself from getting the flu and, failing that, keep it from getting worse if you do get it.

Google flu map
Google's flu map shows data from around the world.


* First off, get a flu shot. You can find out where in your area to get one by using the HealthMap flu-shot finder at the American Lung Association website. Just enter your zip code and find a location that's near you. (And no, even though it's January, it's definitely not too late to get your shot for this season.) See this CDC Q&A on the flu shot.

* See the CDC's flu prevention page for tips on how to avoid getting the flu. You'll recognize most of the commonsense guidelines, which include:
  • wash your hands often with soap and water or a an alcohol-based hand sanitizer; 
  • try not to touch your eyes, nose, or mouth (these are the prime entry points for germs); 
  • and try not to get too close to people who are already sick
Door handles, bathroom fixtures, ATM keypads, and the like harbor abundant number of germs; try touching them only with a paper towel. Also: Computer keyboards are also home to a mind-boggling array of germs. If you have to access a shared keyboard, wipe it down with one of those alcohol-based sheets.

* What if you've gotten the flu already? You probably know the drill: get lots of sleep, drink plenty of fluids, take medication to reduce the fever if you have it, etc. See the Red Cross's information sheet (PDF) for more tips on what to do if you get the flu.

Google is once again doing its Google flu map (see above), which it has done for several years now, so you can see the relative amount of flu activity across the U.S. and around the world.

For some good information (with a humorous touch) on avoiding the flu, see this article from Digital First Media. It includes advice such as getting more sex (it may boost your immune system), avoiding the flu by pretending you're a detective; and even a link to 50 ways to spend your sick day.

Get your flu shot, and stay healthy out there.